Cant speak for the Revolvers but having a 17HMR in a rifle, I will let you know that they destroy what they hit.
Now also, My rifle likes the 20gr Hornady. Not the 17gr.
Way better than the 22mag that's for sure.
edit Correction,,, Cant speak for the Ruger Pistols but I know a few that have the Freedom arms pistols and they are VERY accurate.