Unless one greatly overmatches a bullet to the game intended, there will be a mix between penetration and expansion. Some, not all, tend to overdrive the XTP bullets and tip the favor to expansion. Slowing these bullets down a bit will increase penetration, the same holds true for Ballistic Tip bullets. I have gotten length wise penetration in deer using my .309 JDJ with 150s slowed down to 2,350 fps.
Bullets measuring 0.429" and up are preexpamded prior to pulling the trigger, so I don't worry about trying to drive them so hard. They tend to act more like a flat point cast bullet and make the trip through the shoulders when needed.