When I'm hunting whitetail I just carry my scoped 357 maximum Contender. When hawg hunting I have the Contender but also have my 357 mag on my hip in case a group of them wants to come see me after my initial shot. I recommend having both and letting the situation help you decide what to carry.
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When you were born, you cried and the world rejoiced. Live your life so that when you die, the world cries and you rejoice.