Around 4:30 PM Saturday, I had a lone large doe come in behind me, she was up wind of me and had no idea I was hunting her. She got ever so slightly quartering away and at about 20 yards I shot her. I was using a hand load of 21 grains H-110 and a Swift A-Frame 210 grain bullet with a Fed #155 Primer. Looks like my shot placement was a little back and a little low as I completely took out the lower part of her liver and some of the far side lung. There was hair in the spot where I shot her and I followed her track about 20 yards until I picked up blood. It was a profuse blood trail deep red and at some places watery other places bright red and bubbly. About another 30 yards into the trail I jumped her and she ran. I backed out got some dinner and went back three hours later to find her about 30 yards from where I jumped her, blood trailing was easy. She didn't go 100 yards from where I shot her. The swift A-frame passed through and the liver was destroyed. The DAN WESSON 741 with a green fiber optic front sight did its job. The bullet and the hand load did its job. The doe was recovered and will make fine table fare, but my shot placement should have been about 3-5 inches farther forward for a double lung/heart shot. I am happy with my first ever handgun hunt taking a PA doe.