I am a huge fan of the 10mm I own 7 10mm handguns. I have the 40 with an RMR that gun is fun to shoot is reliable and will hit consistently on a deer size target at 100 yards. Yup it's that much fun. For hunting deer it is my go to gun it rests In a chest style holster from DD. It makes short work of whitetailed deer. I like the 200 grain WFN over some Power Pistol powder. That same gun with a 155 grain XTP over a load of Power Pistol will cut a ragged hole at 25 yards. Also a great deer load to about 75 yards.
Disclaimer; Do not buy a 10mm for you will never be satisfied with one gun the illness that ensues is most difficult to break the fever. The only cure is more and more 10mm guns and ammo.