Just not sure how far a .45 would shoot out too?
Just depends on how far you tilt the barrel up.
If you're leaning toward a revolver, most consider a revolver a 100 yards and closer hunting weapon. I'm by no means saying it's not capable of further ranges in the right hands and correct bullet. The 45 colt, with proper bullet and load, will shoot length ways through a whitetail at 100 yards.
It takes 43 muscles to frown and 17 to smile, but only 3 for proper trigger squeeze.